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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1997 4
1998 7
1999 13
2000 21
2001 28
2002 40
2003 56
2004 57
2005 95
2006 69
2007 72
2008 80
2009 70
2010 90
2011 83
2012 77
2013 108
2014 66
2015 85
2016 80
2017 56
2018 57
2019 41
2020 33
2021 48
2022 19
2023 16
2024 4

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1,337 results

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Page 1
Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation.
Micheau O. Micheau O. Int J Mol Sci. 2018 Mar 2;19(3):715. doi: 10.3390/ijms19030715. Int J Mol Sci. 2018. PMID: 29498673 Free PMC article. Review.
Tumor necrosis-factor related apoptosis-inducing ligand, also known as TRAIL or APO2L (Apo-2 ligand), is a cytokine of the TNF superfamily acknowledged for its ability to trigger selective apoptosis in tumor cells while being relat …
Tumor necrosis-factor related apoptosis-inducing ligand, also known as TRAIL or APO2L (Apo-2 ligand), is …
The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.
Ramamurthy V, Yamniuk AP, Lawrence EJ, Yong W, Schneeweis LA, Cheng L, Murdock M, Corbett MJ, Doyle ML, Sheriff S. Ramamurthy V, et al. Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1273-81. doi: 10.1107/S2053230X15016416. Epub 2015 Sep 23. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26457518 Free PMC article.
The structure of death receptor 4 (DR4) in complex with TNF-related apoptosis-inducing ligand (TRAIL) has been determined at 3 A resolution and compared with those of previously determined DR5-TRAIL complexes. ...
The structure of death receptor 4 (DR4) in complex with TNF-related apoptosis-inducing ligand …
Interleukin-4 Enhances the Sensitivity of Human Monocytes to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Through Upregulation of Death Receptor 4.
Zhang S, Li Z, Huang W. Zhang S, et al. J Interferon Cytokine Res. 2018 Apr;38(4):186-194. doi: 10.1089/jir.2017.0103. Epub 2018 Mar 19. J Interferon Cytokine Res. 2018. PMID: 29638207
However, its role in characteristics of monocytic leukemia cells was rarely reported. In this study, we assessed the role of IL-4 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity of human monocytes. After inc …
However, its role in characteristics of monocytic leukemia cells was rarely reported. In this study, we assessed the role of IL-4 in …
Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 1.
Yoshida T, Yamasaki K, Tadagaki K, Kuwahara Y, Matsumoto A, Sofovic AE, Kondo N, Sakai T, Okuda T. Yoshida T, et al. Int J Oncol. 2022 Jan;60(1):6. doi: 10.3892/ijo.2021.5296. Epub 2021 Dec 27. Int J Oncol. 2022. PMID: 34958111 Free PMC article.
Runt-related transcription factor 1 (RUNX1), which is also known as acute myeloid leukemia 1 (AML1), has been frequently found with genomic aberrations in human leukemia. RUNX1 encodes a transcription factor that can regulate the expression of hematopoietic genes. I …
Runt-related transcription factor 1 (RUNX1), which is also known as acute myeloid leukemia 1 (AML1), has been frequently found with g …
Modulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by Helicobacter pylori in immune pathogenesis of gastric mucosal damage.
Tsai HF, Hsu PN. Tsai HF, et al. J Microbiol Immunol Infect. 2017 Feb;50(1):4-9. doi: 10.1016/j.jmii.2016.01.002. Epub 2016 Jan 29. J Microbiol Immunol Infect. 2017. PMID: 26947589 Free article. Review.
In addition to directly triggering apoptosis, H. pylori induces sensitivity to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in gastric epithelial cells. Human gastric epithelial cells sensitize …
In addition to directly triggering apoptosis, H. pylori induces sensitivity to tumor necrosis factor-related apoptosis- …
TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells.
Heijink DM, Jalving M, Oosterhuis D, Sloots IA, Koster R, Hollema H, Kleibeuker JH, Koornstra JJ, de Vries EG, de Jong S. Heijink DM, et al. J Pathol. 2011 Feb;223(3):378-89. doi: 10.1002/path.2797. Epub 2010 Oct 29. J Pathol. 2011. PMID: 21171083
TNF-related apoptosis-inducing ligand (TRAIL) receptor agonistic agents and non-steroidal anti-inflammatory drugs (NSAIDs) are interesting agents for the chemoprevention and treatment of colorectal cancer. ...Apoptosis levels, expr …
TNF-related apoptosis-inducing ligand (TRAIL) receptor agonistic agents and non-steroidal anti-inf …
TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma.
Keuper M, Wernstedt Asterholm I, Scherer PE, Westhoff MA, Möller P, Debatin KM, Strauss G, Wabitsch M, Fischer-Posovszky P. Keuper M, et al. Cell Death Dis. 2013 Jan 24;4(1):e474. doi: 10.1038/cddis.2012.212. Cell Death Dis. 2013. PMID: 23348588 Free PMC article.
Tumor necrosis factor alpha (TNFalpha) and other members of the TNF family affect adipose tissue metabolism and contribute to the obesity-related inflammation of adipose tissue. Here, we sought to identify the effects of TRAIL (TNF-related apoptosis …
Tumor necrosis factor alpha (TNFalpha) and other members of the TNF family affect adipose tissue metabolism and contribute to the obe …
Overcoming TRAIL Resistance for Glioblastoma Treatment.
Deng L, Zhai X, Liang P, Cui H. Deng L, et al. Biomolecules. 2021 Apr 14;11(4):572. doi: 10.3390/biom11040572. Biomolecules. 2021. PMID: 33919846 Free PMC article. Review.
The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) shows a promising therapeutic potential in cancer treatment as it exclusively causes apoptosis in a broad spectrum of cancer cells through triggering the extrinsic …
The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) shows a promising therapeutic p …
TNF-related apoptosis-inducing ligand (TRAIL) promotes trophoblast cell invasion via miR-146a-EGFR/CXCR4 axis: A novel mechanism for preeclampsia?
Xiao C, Rui Y, Zhou S, Huang Y, Wei Y, Wang Z. Xiao C, et al. Placenta. 2020 Apr;93:8-16. doi: 10.1016/j.placenta.2020.02.011. Epub 2020 Feb 13. Placenta. 2020. PMID: 32090966
INTRODUCTION: Preeclampsia (PE) is associated with failure of uterovascular transformation due to impaired trophoblast invasion. Previously, TNF-related apoptosis-inducing ligand (TRAIL) has been controversially reported to correlate with PE, bu …
INTRODUCTION: Preeclampsia (PE) is associated with failure of uterovascular transformation due to impaired trophoblast invasion. Previously, …
Developing TRAIL/TRAIL death receptor-based cancer therapies.
Yuan X, Gajan A, Chu Q, Xiong H, Wu K, Wu GS. Yuan X, et al. Cancer Metastasis Rev. 2018 Dec;37(4):733-748. doi: 10.1007/s10555-018-9728-y. Cancer Metastasis Rev. 2018. PMID: 29541897 Free PMC article. Review.
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the …
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF super …
1,337 results